Dr.
Viktor Krchnák studied chemistry at the Faculty
of Natural Sciences of the Masaryk University in Brno,
Czechoslovakia. He earned his PhD in organic chemistry
from the Institute of Organic Chemistry and Biochemistry
of the Czechoslovak Academy of Sciences in Prague,
under the supervision of Prof. Zdenek Arnold. After
holding several industrial positions with small biotech
companies in the US, he joined the faculty of the
University of Notre Dame as a research professor in
2003.
His
research interest covers combinatorial chemistry in
general and solid phase chemistry in particular. His
group introduced novel coding technique for the synthesis
on modular solid support (necklace coding), a new
concept for the solid phase synthesis of traceless
heterocyclic libraries, cleavage of resin-bound compounds
by gaseous reagents, the “split-split”
method for the synthesis of sizable combinatorial
libraries (up to 60,000 compounds), and instrumentation
and logistics for high throughput organic synthesis.
A number of his inventions have resulted in commercially
available personal chemistry tools (www.torviq.com).